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Science 27 August 1971:
Vol. 173. no. 3999, pp. 839 - 840
DOI: 10.1126/science.173.3999.839
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Articles

Pineal N-Acetyltransferase Activity: Effect of Sympathetic Stimulation

Paul H. Volkman 1 and Alfred Heller 1

1 Department of Pharmacology, University of chicago, chicago, Illinois

Stimulation of preganglionic sympathetic fibers to the superior cervical ganglia elevates the activity of pineal N-acetyltransferase. After the stimulation-induced rise in enzyme activity, a return toward baseline levels occurs whether or not nerve stimulation is continued. The ability of pineal N-acetyltransferase activity to fall in the presence of stimulation may account for the persistence of its rhythm in blinded animals.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Pineal Gland: 24-Hour Rhythm in Norepinephrine Turnover.
M. Brownstein and J. Axelrod (1974)
Science 184, 163-165
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Science. ISSN 0036-8075 (print), 1095-9203 (online)