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Science 30 July 1971:
Vol. 173. no. 3995, pp. 450 - 452
DOI: 10.1126/science.173.3995.450
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Articles

Melatonin and Abnormal Movements Induced by L-Dopa in Mice

G. C. Cotzias 1, L. C. Tang 1, S. T. Miller 1, and J. Z. Ginos 1

1 Medical Research Center, Brookhaven National Laboratory, Upton, Long Island, New York 11973

Melatonin has blocked adventitious movements induced by L-dopa in intact mice. It has reversed the adventitious turning to the right, and it has induced running to the left in mice receiving L-dopa after a lesion in the right caudate nucleus.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Melatonin protects against 6-OHDA-induced neurotoxicity in rats: a role for mitochondrial complex I activity.
F. DABBENI-SALA, S. DI SANTO, D. FRANCESCHINI, S. D. SKAPER, and P. GIUSTI (2001)
FASEB J 15, 164-170
   Abstract »    Full Text »    PDF »
Melatonin and Parkinsonism.
P. S. Papavasiliou, G. C. Cotzias, S. E. Duby, A. J. Steck, M. Bell, and W. H. Lawrence (1972)
JAMA 221, 88-89
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)