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Science 9 July 1971:
Vol. 173. no. 3992, pp. 146 - 148
DOI: 10.1126/science.173.3992.146
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Articles

In vitro Techniques for Avoiding Edge Damage in Studies of Frog Skin

Sandy I. Helman 1 and David A. Miller 1

1 Department of Physiology, Tulane University School of Medicine, New Orleans, Louisiana 70112

Frog skins mounted between chambers without compression, with a liquid insulator and a tissue adhesive, were studied in vitro. Since voltage and electrical resistance per unit area were unchanged by a tenfold decrease in area of skin studied, it is concluded that these mounting techniques do not produce edge damage and consequently provide a means for study of the skin in its absence.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)