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Science 18 June 1971:
Vol. 172. no. 3989, pp. 1253 - 1256
DOI: 10.1126/science.172.3989.1253
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Articles

Covalent Enzyme-Substrate Intermediates

Robert M. Bell 1 and D. E. Koshland Jr. 1

1 Department of Biochemistry, University of California, Berkeley 94720

A literature search reveals 60 cases in which there is strong evidence for covalent enzyme-substrate intermediates.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Chemistry and Enzymology of kcat Inhibitors.
R. R. Rando (1974)
Science 185, 320-324
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Enzymatic Catalysis and Transition-State Theory.
G. E. Lienhard (1973)
Science 180, 149-154
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Science. ISSN 0036-8075 (print), 1095-9203 (online)