Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 4 June 1971:
Vol. 172. no. 3987, pp. 1047 - 1048
DOI: 10.1126/science.172.3987.1047
Prev | Table of Contents | Next

Articles

Immune Response Restoration with Macrophage Culture Supernatants

M. Hoffmann 1 and R. W. Dutton 1

1 Department of Biology, University of California, San Diego, La Jolla 92037

Depression of the in vitro immune response of mouse spleen cell suspensions to sheep erythrocytes by removal of macrophages can be reversed by the addition of supernatants from peritoneal macrophage cultures. Supernatant activity can be absorbed by the red cell antigen, and supernatant-treated red cells are stimulatory in the absence of macrophages or supernatant.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Restoration of Antibody-Forming Capacity in Cultures of Nonadherent Spleen Cells by Mercaptoethanol.
C. Chen and J. G. Hirsch (1972)
Science 176, 60-61
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)