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Science 28 May 1971:
Vol. 172. no. 3986, pp. 968 - 970
DOI: 10.1126/science.172.3986.968
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Articles

Electroencephalographic and Behavioral Alterations Produced by Dgr1-Tetrahydrocannabinol

Charles H. Hockman 1, Richard G. Perrin 1, and Harold Kalant 1

1 Brain Research Laboratory, Department of Pharmacology, University of Toronto, Toronto 5, Ontario, Canada

The administration of small doses of Dgrl-tetrahydrocannabinol to cats with indwelling electrodes produced a disruption of both the electroencephalogram and behavior. Some of these alterations, including the appearance of a high-voltage slow wave electroencephalogram in the awake and moving animal, have been observed in cats that had been administered other drugs known to cause hallucinogenic states in man.


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