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Science 21 May 1971:
Vol. 172. no. 3985, pp. 859 - 861
DOI: 10.1126/science.172.3985.859
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Articles

Susceptibility of Mink to Sheep Scrapie

Robert P. Hanson 1, Robert J. Eckroade 1, Richard F. Marsh 1, Gabriele M. Zu Rhein 2, Charles L. Kanitz 3, and Donald P. Gustafson 3

1 Department of Veterinary Science, University of Wisconsin, Madison 53706
2 Department of Pathology, University of Wisconsin Medical School, Madison 53706
3 School of Veterinary Science and Medicine, Purdue University, West Lafayette, Indiana 47907

A progressive, fatal spongiform polioencephalopathy was induced in mink intracerebrally inoculated with a suspension of brain from a Suffolk sheep with naturally acquired scrapie. The clinical signs and pathological lesions of the experimental disease were indistinguishable from transmissible mink encephalopathy, a disease of undetermined origin that occurs in mink.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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R. D. Harrington, T. V. Baszler, K. I. O'Rourke, D. A. Schneider, T. R. Spraker, H. D. Liggitt, and D. P. Knowles (2008)
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Breaking an Absolute Species Barrier: Transgenic Mice Expressing the Mink PrP Gene Are Susceptible to Transmissible Mink Encephalopathy.
O. Windl, M. Buchholz, A. Neubauer, W. Schulz-Schaeffer, M. Groschup, S. Walter, S. Arendt, M. Neumann, A. K. Voss, and H. A. Kretzschmar (2005)
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Other animal prion diseases.
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Novel proteinaceous infectious particles cause scrapie.
S. Prusiner (1982)
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Experimental Subacute Spongiform Virus Encephalopathies in Primates and Other Laboratory Animals.
C. J. Gibbs Jr. and D. C. Gajdusek (1973)
Science 182, 67-68
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