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Science 14 May 1971:
Vol. 172. no. 3984, pp. 731 - 733
DOI: 10.1126/science.172.3984.731
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Articles

Vitamin D3: Induction of Calcium-Binding Protein in Embryonic Chick Intestine in vitro

R. A. Corradino 1 and R. H. Wasserman 1

1 Department of Physical Biology, New York State Veterinary College, Cornell University, Ithaca 14850

Induction of the synthesis of calcium-binding protein in chick embryonic intestine maintained in vitro was accomplished by simply adding vitamin D3 to the culture medium. Accompanying the induction of this protein, there was enhanced radiocalcium uptake by the intestine. These observations represent the first demonstration of an in vitro physiological effect of vitamin D3 on the calcium absorptive mechanism of the intestine.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Calcium Absorption and Calcium-Binding Protein Synthesis: Solanum malacoxylon Reverses Strontium Inhibition.
R. H. Wasserman (1974)
Science 183, 1092-1094
   Abstract »    PDF »
Diphenylhydantoin: Effects on Calcium Metabolism in the Chick.
M. Villareale, L. V. Gould, R. H. Wasserman, A. Barr, R. T. Chiroff, and W. H. Bergstrom (1974)
Science 183, 671-673
   Abstract »    PDF »
Embryonic Chick Intestine in Organ Culture: Response to Vitamin D3 and Its Metabolites.
R. A. Corradino (1973)
Science 179, 402-405
   Abstract »    PDF »


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