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Science 14 May 1971:
Vol. 172. no. 3984, pp. 727 - 728
DOI: 10.1126/science.172.3984.727
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Articles

Galactosemia: Evidence for a Structural Gene Mutation

Thomas A. Tedesco 1 and William J. Mellman 2

1 Department of Pediatrics, Hospital of the University of Pennsylvania, Philadelphia 19104
2 Departments of Pediatrics and Medical Genetics, University of Pennsylvania

Identical immunoprecipitin reactions appeared in double immunodiffusion between rabbit anltibodies to human galactose-1-phosphate uridyl transferase and red cell preparations from both normal and galactosemic individuals. The galactosemic erythrocyte preparations quantitatively absorbed the antiboy that immunoprecipitates enzymatically active galactose-1-phosphate uridyl transferase.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Galactose Utilization in Galactosemia.
J. C. Petricciani, M. K. Binder, C. R. Merril, and M. R. Geiter (1972)
Science 175, 1368-1370
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Science. ISSN 0036-8075 (print), 1095-9203 (online)