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Science 30 April 1971:
Vol. 172. no. 3982, pp. 492 - 494
DOI: 10.1126/science.172.3982.492
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Articles

Uncoupling Cell Junctions in a Glandular Epithelium by Depolarizing Current

Sidney J. Socolar 1 and Alberto L. Politoff 1

1 Cell Physics Laboratory, Department of Physiology, College of Physicians and Surgeons, Columbia University, New York 10032

The high electrical conductance linking adjacent border cells in Chironomus salivary gland is depressed reversibly when current is passed outward from one of the cells, though not when current is passed inward. This "uncoupling" is closely associated with an electrically induced increase in conductance in the (nonjunctional) membrane of that cell.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)