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Science 23 April 1971:
Vol. 172. no. 3981, pp. 377 - 379
DOI: 10.1126/science.172.3981.377
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Articles

Theoretical and Experimental Basis for a Specific Countertransport System in Membranes

E. L. Cussler 1, D. Fennell Evans 2, and Sister M. A. Matesich 3

1 Department of Chemical Engineering, Carnegie-Mellon Institute, Pittsburgh, Pennsylvania 15213
2 Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106
3 Department of Chemistry, Ohio Dominican College, Columbus, Ohio

A sodium ion carrier transport system contains the antibiotic monensin in the membrane and uses a pH gradient as an energy source. The experimental results are in accord with theoretical predictions based on a mechanism which is understood on a molecular level.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)