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Science 9 April 1971:
Vol. 172. no. 3979, pp. 163 - 165
DOI: 10.1126/science.172.3979.163
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Articles

2-Thiophenecarboxylic Acid: Inhibitor of Bone Resorption in Tissue Culture

Victor S. Fang 1, Cedric Minkin 1, and Paul Goldhaber 1

1 Departments of Pharmacology, Oral Biology and Pathophysiology, and Periodontology, Harvard School of Dental Medicine, Boston, Massachusetts 02115

In tissue culture 2-thiophenecarboxylic acid inhibited both spontaneous resorption of bone and that induced by parathyroid hormone. Its action was to inhibit calcium transfer out of bone.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Carbonic Anhydrase and Bone Remodeling: Sulfonamide Inhibition of Bone Resorption in Organ Culture.
C. Minkin and J. M. Jennings (1972)
Science 176, 1031-1033
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Science. ISSN 0036-8075 (print), 1095-9203 (online)