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Science 8 January 1971:
Vol. 171. no. 3966, pp. 66 - 68
DOI: 10.1126/science.171.3966.66
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Articles

Pulmonary Compliance: Alteration during Infection

Norman L. Somerson 1, Stella B. Kontras 1, J. Dennis Pollack 1, and Harold S. Weiss 1

1 Departments of Medical Microbiology, Pediatrics, and Physiology, Ohio State University, Columbus 43210

Lungs excised from rats infected with Mycoplasma pulmonis are more difficult to inflate with air than those from uninfected animals; they show no significant differences from controls inflated with saline. The altered pulmonary function in lungs from infected rats is attributed to an increase in surface forces, implying disruption of the lung surfactant system.


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