Science 4 December 1970: Vol. 170. no. 3962, pp. 1095 - 1096 DOI: 10.1126/science.170.3962.1095

Prev | Table of Contents | Next

Articles

Identification of a New Exosite Involved in Catalytic Turnover by the Streptokinase-Plasmin Activator Complex during Human Plasminogen Activation.

R. Aneja, M. Datt, B. Singh, S. Kumar, and G. Sahni (2009)
J. Biol. Chem. 284, 32642-32650
 |  Abstract »  |  Full Text »  |  PDF »

The Urokinase Receptor Promotes Cancer Metastasis Independently of Urokinase-Type Plasminogen Activator in Mice.

M. Jo, S. Takimoto, V. Montel, and S. L. Gonias (2009)
Am. J. Pathol. 175, 190-200
 |  Abstract »  |  Full Text »  |  PDF »

Rapid-reaction Kinetic Characterization of the Pathway of Streptokinase-Plasmin Catalytic Complex Formation.

I. M. Verhamme and P. E. Bock (2008)
J. Biol. Chem. 283, 26137-26147
 |  Abstract »  |  Full Text »  |  PDF »

Factor Xa Binding to Annexin 2 Mediates Signal Transduction via Protease-Activated Receptor 1.

G. Bhattacharjee, J. Ahamed, R. Pawlinski, C. Liu, N. Mackman, W. Ruf, and T. S. Edgington (2008)
Circ. Res. 102, 457-464
 |  Abstract »  |  Full Text »  |  PDF »

{alpha}-Enolase Resides on the Cell Surface of Mycoplasma fermentans and Binds Plasminogen.

A. Yavlovich, H. Rechnitzer, and S. Rottem (2007)
Infect. Immun. 75, 5716-5719
 |  Abstract »  |  Full Text »  |  PDF »

Plasminogen Structural Domains Exhibit Different Functions When Associated with Cell Surface GRP78 or the Voltage-dependent Anion Channel.

M. Gonzalez-Gronow, S. J. Kaczowka, S. Payne, F. Wang, G. Gawdi, and S. V. Pizzo (2007)
J. Biol. Chem. 282, 32811-32820
 |  Abstract »  |  Full Text »  |  PDF »

Thrombin-activable Fibrinolysis Inhibitor (TAFI) Zymogen Is an Active Carboxypeptidase.

Z. Valnickova, I. B. Thogersen, J. Potempa, and J. J. Enghild (2007)
J. Biol. Chem. 282, 3066-3076
 |  Abstract »  |  Full Text »  |  PDF »

Integrin {alpha}Dbeta2, an adhesion receptor up-regulated on macrophage foam cells, exhibits multiligand-binding properties.

V. P. Yakubenko, S. P. Yadav, and T. P. Ugarova (2006)
Blood 107, 1643-1650
 |  Abstract »  |  Full Text »  |  PDF »

Association of Plasminogen with Dipeptidyl Peptidase IV and Na+/H+ Exchanger Isoform NHE3 Regulates Invasion of Human 1-LN Prostate Tumor Cells.

M. Gonzalez-Gronow, U. K. Misra, G. Gawdi, and S. V. Pizzo (2005)
J. Biol. Chem. 280, 27173-27178
 |  Abstract »  |  Full Text »  |  PDF »

Effects of dietary vitamin A intake on acrosin- and plasminogen-activator activity of ram spermatozoa.

I A Zervos, M P Tsantarliotou, G Vatzias, P Goulas, N A Kokolis, and I A Taitzoglou (2005)
Reproduction 129, 707-715
 |  Abstract »  |  Full Text »  |  PDF »

Bacillolysin MA, a Novel Bacterial Metalloproteinase That Produces Angiostatin-like Fragments from Plasminogen and Activates Protease Zymogens in the Coagulation and Fibrinolysis Systems.

R. Narasaki, H. Kuribayashi, K. Shimizu, D. Imamura, T. Sato, and K. Hasumi (2005)
J. Biol. Chem. 280, 14278-14287
 |  Abstract »  |  Full Text »  |  PDF »

Tissue plasminogen activator promotes the effects of corticotropin-releasing factor on the amygdala and anxiety-like behavior.

T. Matys, R. Pawlak, E. Matys, C. Pavlides, B. S. McEwen, and S. Strickland (2004)
PNAS 101, 16345-16350
 |  Abstract »  |  Full Text »  |  PDF »

Phospholipid Barrier to Fibrinolysis: ROLE FOR THE ANIONIC POLAR HEAD CHARGE AND THE GEL PHASE CRYSTALLINE STRUCTURE.

B. Varadi, K. Kolev, K. Tenekedjiev, G. Meszaros, I. Kovalszky, C. Longstaff, and R. Machovich (2004)
J. Biol. Chem. 279, 39863-39871
 |  Abstract »  |  Full Text »  |  PDF »

Mycoplasma fermentans Binds to and Invades HeLa Cells: Involvement of Plasminogen and Urokinase.

A. Yavlovich, A. Katzenell, M. Tarshis, A. A.-R. Higazi, and S. Rottem (2004)
Infect. Immun. 72, 5004-5011
 |  Abstract »  |  Full Text »  |  PDF »

Resolution of Conformational Activation in the Kinetic Mechanism of Plasminogen Activation by Streptokinase.

P. D. Boxrud, I. M. Verhamme, and P. E. Bock (2004)
J. Biol. Chem. 279, 36633-36641
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of plasminogen as an adhesive ligand for integrins {alpha}M{beta}2 (Mac-1) and {alpha}5{beta}1 (VLA-5).

V. K. Lishko, V. V. Novokhatny, V. P. Yakubenko, H. V. Skomorovska-Prokvolit, and T. P. Ugarova (2004)
Blood 104, 719-726
 |  Abstract »  |  Full Text »  |  PDF »

Cell Surface Adenosine Deaminase Binds and Stimulates Plasminogen Activation on 1-LN Human Prostate Cancer Cells.

M. Gonzalez-Gronow, M. S. Hershfield, F. X. Arredondo-Vega, and S. V. Pizzo (2004)
J. Biol. Chem. 279, 20993-20998
 |  Abstract »  |  Full Text »  |  PDF »

Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis.

K. Akassoglou, R. A. Adams, J. Bauer, P. Mercado, V. Tseveleki, H. Lassmann, L. Probert, and S. Strickland (2004)
PNAS 101, 6698-6703
 |  Abstract »  |  Full Text »  |  PDF »

Protease Nexin-1 Inhibits Plasminogen Activation-induced Apoptosis of Adherent Cells.

P. Rossignol, B. Ho-Tin-Noe, R. Vranckx, M.-C. Bouton, O. Meilhac, H. R. Lijnen, M.-C. Guillin, J.-B. Michel, and E. Angles-Cano (2004)
J. Biol. Chem. 279, 10346-10356
 |  Abstract »  |  Full Text »  |  PDF »

Generation and Characterization of a Highly Stable Form of Activated Thrombin-activable Fibrinolysis Inhibitor.

P. F. Marx, S. R. Havik, J. A. Marquart, B. N. Bouma, and J. C. M. Meijers (2004)
J. Biol. Chem. 279, 6620-6628
 |  Abstract »  |  Full Text »  |  PDF »

Identification and Characterization of Novel Lysine-independent Apolipoprotein(a)-binding Sites in Fibrin(ogen) {alpha}C-domains.

G. Tsurupa, B. Ho-Tin-Noe, E. Angles-Cano, and L. Medved (2003)
J. Biol. Chem. 278, 37154-37159
 |  Abstract »  |  Full Text »  |  PDF »

Domain Truncation Studies Reveal That the Streptokinase-Plasmin Activator Complex Utilizes Long Range Protein-Protein Interactions with Macromolecular Substrate to Maximize Catalytic Turnover.

V. Sundram, J. S. Nanda, K. Rajagopal, J. Dhar, A. Chaudhary, and G. Sahni (2003)
J. Biol. Chem. 278, 30569-30577
 |  Abstract »  |  Full Text »  |  PDF »

The Voltage-dependent Anion Channel Is a Receptor for Plasminogen Kringle 5 on Human Endothelial Cells.

M. Gonzalez-Gronow, T. Kalfa, C. E. Johnson, G. Gawdi, and S. V. Pizzo (2003)
J. Biol. Chem. 278, 27312-27318
 |  Abstract »  |  Full Text »  |  PDF »

Structure-Function Analysis of the Streptokinase Amino Terminus (Residues 1-59).

L. V. Mundada, M. Prorok, M. E. DeFord, M. Figuera, F. J. Castellino, and W. P. Fay (2003)
J. Biol. Chem. 278, 24421-24427
 |  Abstract »  |  Full Text »  |  PDF »

Amyloid Endostatin Induces Endothelial Cell Detachment by Stimulation of the Plasminogen Activation System.

A. Reijerkerk, L. O. Mosnier, O. Kranenburg, B. N. Bouma, P. Carmeliet, T. Drixler, J. C.M. Meijers, E. E. Voest, and M. F.B.G. Gebbink (2003)
Mol. Cancer Res. 1, 561-568
 |  Abstract »  |  Full Text »  |  PDF »

Myosin: a noncovalent stabilizer of fibrin in the process of clot dissolution.

K. Kolev, K. Tenekedjiev, K. Ajtai, I. Kovalszky, J. Gombas, B. Varadi, and R. Machovich (2003)
Blood 101, 4380-4386
 |  Abstract »  |  Full Text »  |  PDF »

Distinct dose-dependent effects of plasmin and TPA on coagulation and hemorrhage.

D. Stewart, M. Kong, V. Novokhatny, G. Jesmok, and V. J. Marder (2003)
Blood 101, 3002-3007
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Rac1 activation by the low density lipoprotein receptor-related protein.

Z. Ma, K. S. Thomas, D. J. Webb, R. Moravec, A. M. Salicioni, W. M. Mars, and S. L. Gonias (2002)
J. Cell Biol. 159, 1061-1070
 |  Abstract »  |  Full Text »  |  PDF »

Acyl-Enzyme Complexes between Tissue-type Plasminogen Activator and Neuroserpin are Short-lived in Vitro.

K. Barker-Carlson, D. A. Lawrence, and B. S. Schwartz (2002)
J. Biol. Chem. 277, 46852-46857
 |  Abstract »  |  Full Text »  |  PDF »

Collagen Dissolution by Keratinocytes Requires Cell Surface Plasminogen Activation and Matrix Metalloproteinase Activity.

S. Netzel-Arnett, D. J. Mitola, S. S. Yamada, K. Chrysovergis, K. Holmbeck, H. Birkedal-Hansen, and T. H. Bugge (2002)
J. Biol. Chem. 277, 45154-45161
 |  Abstract »  |  Full Text »  |  PDF »

Effects of deletion of streptokinase residues 48-59 on plasminogen activation.

N. Wakeham, S. Terzyan, P. Zhai, J.A. Loy, J. Tang, and X.C. Zhang (2002)
Protein Eng. Des. Sel. 15, 753-761
 |  Abstract »  |  Full Text »  |  PDF »

Lp(a) Particles Mold Fibrin-Binding Properties of Apo(a) in Size-Dependent Manner: A Study With Different-Length Recombinant Apo(a), Native Lp(a), and Monoclonal Antibody.

C. Kang, M. Dominguez, S. Loyau, T. Miyata, V. Durlach, and E. Angles-Cano (2002)
Arterioscler Thromb Vasc Biol 22, 1232-1238
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of a Nine-residue Loop of Streptokinase in the Generation of Macromolecular Substrate Specificity by the Activator Complex through Interaction with Substrate Kringle Domains.

J. Dhar, A. H. Pande, V. Sundram, J. S. Nanda, S. C. Mande, and G. Sahni (2002)
J. Biol. Chem. 277, 13257-13267
 |  Abstract »  |  Full Text »  |  PDF »

The Accumulation of Angiostatin-like Fragments in Human Prostate Carcinoma.

T. Migita, Y. Oda, S. Naito, W. Morikawa, M. Kuwano, and M. Tsuneyoshi (2001)
Clin. Cancer Res. 7, 2750-2756
 |  Abstract »  |  Full Text »  |  PDF »

The impaired polymerization of fibrinogen Longmont (B{beta}166Arg{right-arrow}Cys) is not improved by removal of disulfide-linked dimers from a mixture of dimers and cysteine-linked monomers.

K. C. Lounes, J. B. Lefkowitz, A. H. Henschen-Edman, A. I. Coates, R. R. Hantgan, and S. T. Lord (2001)
Blood 98, 661-666
 |  Abstract »  |  Full Text »  |  PDF »

Fibrinogen Milano XII: a dysfunctional variant containing 2 amino acid substitutions, A{alpha} R16C and {gamma} G165R.

B. Bolliger-Stucki, S. T. Lord, and M. Furlan (2001)
Blood 98, 351-357
 |  Abstract »  |  Full Text »  |  PDF »

Depletion of circulating {alpha}2-antiplasmin by intravenous plasmin or immunoneutralization reduces focal cerebral ischemic injury in the absence of arterial recanalization.

N. Nagai, M. De Mol, B. Van Hoef, M. Verstreken, and D. Collen (2001)
Blood 97, 3086-3092
 |  Abstract »  |  Full Text »  |  PDF »

Plasminogen Binding and Activation by Mycoplasma fermentans.

A. Yavlovich, A. A.-R. Higazi, and S. Rottem (2001)
Infect. Immun. 69, 1977-1982
 |  Abstract »  |  Full Text »  |  PDF »

Development of Antibody Against Epitope of Lipoprotein(a) Modified by Oxidation : Evaluation of New Enzyme-Linked Immunosorbent Assay for Oxidized Lipoprotein(a).

S. Yamada, R. Morishita, S. Nakamura, T. Ogihara, Y. Kusumi, I. Sakurai, N. Kubo, and I. Sakurabayashi (2000)
Circulation 102, 1639-1644
 |  Abstract »  |  Full Text »  |  PDF »

Tissue Plasminogen Activator-Mediated Fibrinolysis Protects against Axonal Degeneration and Demyelination after Sciatic Nerve Injury.

K. Akassoglou, K. W. Kombrinck, J. L. Degen, and S. Strickland (2000)
J. Cell Biol. 149, 1157-1166
 |  Abstract »  |  Full Text »  |  PDF »

Effect of Individual Plasma Lipoprotein(a) Variations In Vivo on Its Competition With Plasminogen for Fibrin and Cell Binding : An In Vitro Study Using Plasma From Children With Idiopathic Nephrotic Syndrome.

T. Soulat, S. Loyau, V. Baudouin, L. Maisonneuve, M.-F. Hurtaud-Roux, N. Schlegel, C. Loirat, and E. Angles-Cano (2000)
Arterioscler Thromb Vasc Biol 20, 575-584
 |  Abstract »  |  Full Text »  |  PDF »

Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion.

D. Webb, D. Nguyen, and S. Gonias (2000)
J. Cell Sci. 113, 123-134
 |  Abstract »  |  PDF »

Cloning, Expression, Sequence Analysis, and Characterization of Streptokinases Secreted by Porcine and Equine Isolates of Streptococcus equisimilis.

A. R. Caballero, R. Lottenberg, and K. H. Johnston (1999)
Infect. Immun. 67, 6478-6486
 |  Abstract »  |  Full Text »  |  PDF »

Neuronal Death and Blood-Brain Barrier Breakdown after Excitotoxic Injury Are Independent Processes.

Z.-l. Chen, J. A. Indyk, T. H. Bugge, K. W. Kombrinck, J. L. Degen, and S. Strickland (1999)
J. Neurosci. 19, 9813-9820
 |  Abstract »  |  Full Text »  |  PDF »

Assay of Procarboxypeptidase U, a Novel Determinant of the Fibrinolytic Cascade, in Human Plasma.

K. A. Schatteman, F. J. Goossens, S. S. Scharpe, H. M. Neels, and D. F. Hendriks (1999)
Clin. Chem. 45, 807-813
 |  Abstract »  |  Full Text »  |  PDF »

Two Distinct Urokinase-Serpin Interactions Regulate the Initiation of Cell Surface-associated Plasminogen Activation.

B. S. Schwartz and F. Espana (1999)
J. Biol. Chem. 274, 15278-15283
 |  Abstract »  |  Full Text »  |  PDF »

Angiostatin binds ATP synthase on the surface of human endothelial cells.

T. L. Moser, M. S. Stack, I. Asplin, J. J. Enghild, P. Hojrup, L. Everitt, S. Hubchak, H. W. Schnaper, and S. V. Pizzo (1999)
PNAS 96, 2811-2816
 |  Abstract »  |  Full Text »  |  PDF »

Staphylokinase as a Plasminogen Activator Component in Recombinant Fusion Proteins.

S. J. Szarka, E. G. Sihota, H. R. Habibi, and S.-L. Wong (1999)
Appl. Envir. Microbiol. 65, 506-513
 |  Abstract »  |  Full Text »

Multiple Forms of Angiostatin Induce Apoptosis in Endothelial Cells.

R. Lucas, L. Holmgren, I. Garcia, B. Jimenez, S.J. Mandriota, F. Borlat, B.K.L. Sim, Z. Wu, G.E. Grau, Y. Shing, et al. (1998)
Blood 92, 4730-4741
 |  Abstract »  |  Full Text »  |  PDF »

Prothrombin Kringle-2 Domain Has a Growth Inhibitory Activity against Basic Fibroblast Growth Factor-stimulated Capillary Endothelial Cells.

T.-H. Lee, T. Rhim, and S. S. Kim (1998)
J. Biol. Chem. 273, 28805-28812
 |  Abstract »  |  Full Text »  |  PDF »

Human Procarboxypeptidase U, or Thrombin-activable Fibrinolysis Inhibitor, Is a Substrate for Transglutaminases. EVIDENCE FOR TRANSGLUTAMINASE-CATALYZED CROSS-LINKING TO FIBRIN.

Z. Valnickova and J. J. Enghild (1998)
J. Biol. Chem. 273, 27220-27224
 |  Abstract »  |  Full Text »  |  PDF »

Lysis of Plasma Clots by Urokinase-Soluble Urokinase Receptor Complexes.

A. A.-R. Higazi, K. Bdeir, E. Hiss, S. Arad, A. Kuo, I. Barghouti, and D. B. Cines (1998)
Blood 92, 2075-2083
 |  Abstract »  |  Full Text »  |  PDF »

NH2-terminal Structural Motifs in Staphylokinase Required for Plasminogen Activation.

B. Schlott, K.-H. Guhrs, M. Hartmann, A. Rocker, and D. Collen (1998)
J. Biol. Chem. 273, 22346-22350
 |  Abstract »  |  Full Text »  |  PDF »

Flow Rate–Modulated Dissolution of Fibrin With Clot-Embedded and Circulating Proteases.

E. Komorowicz, K. Kolev, I. Lerant, and R. Machovich (1998)
Circ. Res. 82, 1102-1108
 |  Abstract »  |  Full Text »  |  PDF »

Tissue Factor Regulates Plasminogen Binding and Activation.

Z. Fan, P. J. Larson, J. Bognacki, P.N. Raghunath, J. E. Tomaszewski, A. Kuo, G. Canziani, I. Chaiken, D. B. Cines, and A. A.-R. Higazi (1998)
Blood 91, 1987-1998
 |  Abstract »  |  Full Text »  |  PDF »

Engineering of Plasmin-Resistant Forms of Streptokinase and Their Production in Bacillus subtilis: Streptokinase with Longer Functional Half-Life.

X.-C. Wu, R. Ye, Y. Duan, and S.-L. Wong (1998)
Appl. Envir. Microbiol. 64, 824-829
 |  Abstract »  |  Full Text »

Plasminogen Activation by Streptokinase via a Unique Mechanism.

K.-C. Young, G.-Y. Shi, D.-H. Wu, L.-C. Chang, B.-I. Chang, C.-P. Ou, and H.-L. Wu (1998)
J. Biol. Chem. 273, 3110-3116
 |  Abstract »  |  Full Text »  |  PDF »

Lipoprotein(a) Isoforms Display Differences in Affinity for Plasminogen-Like Binding to Human Mononuclear Cells.

C. Kang, V. Durlach, T. Soulat, C. Fournier, and E. Angles-Cano (1997)
Arterioscler Thromb Vasc Biol 17, 2036-2043
 |  Abstract »  |  Full Text »

Kringle 5 of Plasminogen is a Novel Inhibitor of Endothelial Cell Growth.

Y. Cao, A. Chen, S. S. A. An, R.-W. Ji, D. Davidson, Y. Cao, and M. Llinas (1997)
J. Biol. Chem. 272, 22924-22928
 |  Abstract »  |  Full Text »  |  PDF »

Embryonic Fibroblasts That Are Genetically Deficient in Low Density Lipoprotein Receptor-related Protein Demonstrate Increased Activity of the Urokinase Receptor System and Accelerated Migration on Vitronectin.

A. M. Weaver, I. M. Hussaini, A. Mazar, J. Henkin, and S. L. Gonias (1997)
J. Biol. Chem. 272, 14372-14379
 |  Abstract »  |  Full Text »  |  PDF »

Functional Evaluation of the Structural Features of Proteases and Their Substrate in Fibrin Surface Degradation.

K. Kolev, K. Tenekedjiev, E. Komorowicz, and R. Machovich (1997)
J. Biol. Chem. 272, 13666-13675
 |  Abstract »  |  Full Text »  |  PDF »

Staphylokinase Requires NH2-terminal Proteolysis for Plasminogen Activation.

B. Schlott, K.-H. Guhrs, M. Hartmann, A. Rocker, and D. Collen (1997)
J. Biol. Chem. 272, 6067-6072
 |  Abstract »  |  Full Text »  |  PDF »

Production and Characterization of Recombinant Human Plasminogen(S741C-Fluorescein). A NOVEL APPROACH TO STUDY ZYMOGEN ACTIVATION WITHOUT GENERATION OF ACTIVE PROTEASE.

A. J.G. Horrevoets, H. Pannekoek, and M. E. Nesheim (1997)
J. Biol. Chem. 272, 2176-2182
 |  Abstract »  |  Full Text »  |  PDF »

Fibronectin provides a conduit for fibroblast transmigration from collagenous stroma into fibrin clot provisional matrix.

D Greiling and R. Clark (1997)
J. Cell Sci. 110, 861-870
 |  Abstract »  |  PDF »

Complement C5b-9 Increases Plasminogen Binding and Activation on Human Endothelial Cells.

V. J. Christiansen, P. J. Sims, and K. K. Hamilton (1997)
Arterioscler Thromb Vasc Biol 17, 164-171
 |  Abstract »  |  Full Text »

Molecular Pathogenesis of Type I Congenital Plasminogen Deficiency: Expression of Recombinant Human Mutant Plasminogens in Mammalian Cells.

H. Azuma, N. Mima, M. Shirakawa, K. Miyamoto, H. Yamaguchi, T. Mitsui, T. Shigekiyo, and S. Saito (1997)
Blood 89, 183-190
 |  Abstract »  |  Full Text »  |  PDF »

Cell-surface Cytokeratin 8Is the Major Plasminogen Receptor on Breast Cancer Cells and Is Required for the Accelerated Activation of Cell-associated Plasminogen by Tissue-type Plasminogen Activator.

T. A. Hembrough, L. Li, and S. L. Gonias (1996)
J. Biol. Chem. 271, 25684-25691
 |  Abstract »  |  Full Text »  |  PDF »

Defensin Modulates Tissue-type Plasminogen Activator and Plasminogen Binding to Fibrin and Endothelial Cells.

A. A.-R. Higazi, T. Ganz, K. Kariko, and D. B. Cines (1996)
J. Biol. Chem. 271, 17650-17655
 |  Abstract »  |  Full Text »  |  PDF »

Recombinant Staphylokinase Variants With Altered Immunoreactivity: I: Construction and Characterization.

D. Collen, R. Bernaerts, P. Declerck, F. De Cock, E. Demarsin, S. Jenne, Y. Laroche, H. R. Lijnen, K. Silence, and M. Verstreken (1996)
Circulation 94, 197-206
 |  Abstract »  |  Full Text »

Activated Human Plasma Carboxypeptidase B Is Retained in the Blood by Binding to alpha 2-Macroglobulin and Pregnancy Zone Protein.

Z. Valnickova, I. B. Thogersen, S. Christensen, C. T. Chu, S. V. Pizzo, and J. J. Enghild (1996)
J. Biol. Chem. 271, 12937-12943
 |  Abstract »  |  Full Text »  |  PDF »

Inhibitors of Fibrinolysis Are Elevated in Atherosclerotic Plaque.

L. A. Robbie, N. A. Booth, P. A.J. Brown, and B. Bennett (1996)
Arterioscler Thromb Vasc Biol 16, 539-545
 |  Abstract »  |  Full Text »

Analogs of Human Plasminogen That Are Labeled with Fluorescence Probes at the Catalytic Site of the Zymogen.

P. E. Bock, D. E. Day, I. M. A. Verhamme, M. M. Bernardo, S. T. Olson, and J. D. Shore (1996)
J. Biol. Chem. 271, 1072-1080
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of Streptokinase and Plasminogen.

K.-C. Young, G.-Y. Shi, Y.-F. Chang, B.-I. Chang, L.-C. Chang, M.-D. Lai, W.-J. Chuang, and H.-L. Wu (1995)
J. Biol. Chem. 270, 29601-29606
 |  Abstract »  |  Full Text »  |  PDF »

Structure-Function Relationships in Staphylokinase as Revealed by ``Clustered Charge to Alanine'' Mutagenesis.

K. Silence, M. Hartmann, K.-H. Gührs, A. Gase, B. Schlott, Dés. Collen, and , H. R. Lijnen (1995)
J. Biol. Chem. 270, 27192-27198
 |  Abstract »  |  Full Text »  |  PDF »

Superficial Accumulation of Plasminogen During Plasma Clot Lysis.

D. V. Sakharov and D. C. Rijken (1995)
Circulation 92, 1883-1890
 |  Abstract »  |  Full Text »

Interleukin-1-Mediated Regulation of Plasminogen Activation in Pregnant Mare Serum Gonadotropin-Primed Rat Granulosa Cells Is Independent of Prostaglandin Production.

A. Hurwitz, Z. Finci-Yeheskel, M. Dushnik, A. Milwidsky, S. Shimonovitz, S. Yagel, E. Y. Adashi, and M. Mayer (1995)
Reproductive Sciences 2, 691-699
 |  Abstract »  |  PDF »

Interaction of Single-chain Urokinase and Plasminogen Activator Inhibitor Type 1.

N. Manchanda and B. S. Schwartz (1995)
J. Biol. Chem. 270, 20032-20035
 |  Abstract »  |  Full Text »  |  PDF »

Identification of an Inhibitor of Tissue-type Plasminogen Activator-mediated Fibrinolysis in Human Neutrophils.

A. A.-R. Higazi, I. I. Barghouti, and R. Abu-Much (1995)
J. Biol. Chem. 270, 9472-9477
 |  Abstract »  |  Full Text »  |  PDF »

Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction..

T H Bugge, M J Flick, C C Daugherty, and J L Degen (1995)
Genes & Dev. 9, 794-807
 |  Abstract »  |  PDF »

A cytokeratin 8-like protein with plasminogen-binding activity is present on the external surfaces of hepatocytes, HepG2 cells and breast carcinoma cell lines.

T. Hembrough, J Vasudevan, M. Allietta, W. Glass, and S. Gonias (1995)
J. Cell Sci. 108, 1071-1082
 |  Abstract »  |  PDF »

Angiostatin: A Circulating Endothelial Cell Inhibitor That Suppresses Angiogenesis and Tumor Growth.

M.S. O'Reilly, L. Holmgren, Y. Shing, C. Chen, R.A. Rosenthal, Y. Cao, M. Moses, W.S. Lane, E.H. Sage, and J. Folkman (1994)
Cold Spring Harb Symp Quant Biol 59, 471-482
 |  Abstract »  |  PDF »

Basic Biological Sciences: Retinoic Acid Stimulates Degradation of Interstitial Collagen Fibrils by Rat Mucosal Keratinocytes in vitro.

B.R. Wells and H. Birkedal-Hansen (1985)
Journal of Dental Research 64, 1186-1190
 |  Abstract »  |  PDF »

Antibody-directed urokinase: a specific fibrinolytic agent.

C Bode, G. Matsueda, K. Hui, and E Haber (1985)
Science 229, 765-767
 |  Abstract »  |  PDF »

Ethyl Alcohol Enhances Plasminogen Activator Secretion by Endothelial Cells.

W. E. Laug (1983)
JAMA 250, 772-776
 |  Abstract »  |  PDF »

Plaminogen is synthesized by primary cultures of rat hepatocytes.

J. Bohmfalk and G. Fuller (1980)
Science 209, 408-410
 |  Abstract »  |  PDF »

New Assay for the Plasminogen Activator Activity of Transformed Cells.

W. F. Mangel, D. C. Livingston, J. R. Brocklehurst, H.-Y. Liu, G. A. Peltz, J. F. Cannon, S. P. Leytus, J. A. Wehrly, B. L. Salter, and J. L. Mosher (1980)
Cold Spring Harb Symp Quant Biol 44, 669-680
 |  Abstract »  |  PDF »

Recombinant Fibrinogen Vlissingen/Frankfurt IV. THE DELETION OF RESIDUES 319 AND 320 FROM THE gamma CHAIN OF FIBRINOGEN ALTERS CALCIUM BINDING, FIBRIN POLYMERIZATION, CROSS-LINKING, AND PLATELET AGGREGATION.

K. A. Hogan, O. V. Gorkun, K. C. Lounes, A. I. Coates, J. W. Weisel, R. R. Hantgan, and S. T. Lord (2000)
J. Biol. Chem. 275, 17778-17785
 |  Abstract »  |  Full Text »  |  PDF »

Purification, Cloning, and Characterization of a Profibrinolytic Plasminogen-binding Protein, TIP49a.

S. B. Hawley, T.-a. Tamura, and L. A. Miles (2001)
J. Biol. Chem. 276, 179-186
 |  Abstract »  |  Full Text »  |  PDF »

Coiled Coil Region of Streptokinase gamma -Domain Is Essential for Plasminogen Activation.

D.-H. Wu, G.-Y. Shi, W.-J. Chuang, J.-M. Hsu, K.-C. Young, C.-W. Chang, and H.-L. Wu (2001)
J. Biol. Chem. 276, 15025-15033
 |  Abstract »  |  Full Text »  |  PDF »

The Mechanism of a Bacterial Plasminogen Activator Intermediate between Streptokinase and Staphylokinase.

I. Y. Sazonova, A. K. Houng, S. A. Chowdhry, B. R. Robinson, L. Hedstrom, and G. L. Reed (2001)
J. Biol. Chem. 276, 12609-12613
 |  Abstract »  |  Full Text »  |  PDF »

Proteolytic Cleavage of Chromogranin A (CgA) by Plasmin. SELECTIVE LIBERATION OF A SPECIFIC BIOACTIVE CgA FRAGMENT THAT REGULATES CATECHOLAMINE RELEASE.

Q. Jiang, L. Taupenot, S. K. Mahata, M. Mahata, D. T. O'Connor, L. A. Miles, and R. J. Parmer (2001)
J. Biol. Chem. 276, 25022-25029
 |  Abstract »  |  Full Text »  |  PDF »

The Profibrinolytic Enzyme Subtilisin NAT Purified from Bacillus subtilis Cleaves and Inactivates Plasminogen Activator Inhibitor Type 1.

T. Urano, H. Ihara, K. Umemura, Y. Suzuki, M. Oike, S. Akita, Y. Tsukamoto, I. Suzuki, and A. Takada (2001)
J. Biol. Chem. 276, 24690-24696
 |  Abstract »  |  Full Text »  |  PDF »

Crystal structure of native chicken fibrinogen at 5.5-A resolution.

Z. Yang, I. Mochalkin, L. Veerapandian, M. Riley, and R. F. Doolittle (2000)
PNAS 97, 3907-3912
 |  Abstract »  |  Full Text »  |  PDF »

To Advertise   |   Find Products