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Science 6 November 1970:
Vol. 170. no. 3958, pp. 637 - 639
DOI: 10.1126/science.170.3958.637
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Articles

Tuberculin-Active Carbohydrate That Induces Inhibition of Macrophage Migration but not Lymphocyte Transformation

Sotiros D. Chaparas 1, Daniel E. Thor 1, H. P. Godfrey 1, Harold Baer 1, and Sally R. Hedrick 1

1 Division of Biologics Standards, National Institutes of Health, Bethesda, Maryland 20014

A tuberculin carbohydrate fraction, GAE, in sensitized animals induced a delayed type of skin reactivity and inhibited the migration of macrophages but failed to stimulate lymphocyte transformation in vitro. Tuberculin protein-containing fractions were active in each test. These results show that in vitro lymphocyte transformation is not necessarily a corollary of delayed type hypersensitivity.


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Intrasinusoidal Metastatic Melanoma of the Liver With Reactive Hepatitis: An Immunologic Phenomenon?.
G. Delpre, S. Pitlik, J. Halevy, G. Perry, I. Avidor, U. Kadish, and J. Rosenfeld (1983)
Arch Intern Med 143, 363-365
   Abstract »    PDF »
Cell-Mediated Hypersensitivity to Neural Antigens: Occurrence in Human Patients and Nonhuman Primates With Neurological Diseases.
P. O. Behan, W. M. H. Behan, R. G. Feldman, and M. W. Kies (1972)
Arch Neurol 27, 145-152
   Abstract »    PDF »


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