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Science 30 October 1970:
Vol. 170. no. 3957, pp. 550 - 551
DOI: 10.1126/science.170.3957.550
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Articles

Antibody to Nuclear Material Eluted from Isolated Spleen Vessels in Systemic Lupus Erythematosus

Kathryn H. Svec 1 and Susan T. Allen 1

1 Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106

Splenic blood vessels were isolated from surrounding cells by treatment with trypsin and the use of ultrasound. This procedure retained vascular-bound immunoglobulins which were recovered by acid elution of vessels isolated from a patient with systemic lupus erythematosus. These eluted immunoglobulins reacted with material from cell nuclei as demonstrated by immunofluorescence.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Section 8: Systemic Lupus Erythematosus.
(1973)
JAMA 224, 701-711
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Science. ISSN 0036-8075 (print), 1095-9203 (online)