Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 23 October 1970:
Vol. 170. no. 3956, pp. 452 - 453
DOI: 10.1126/science.170.3956.452
Prev | Table of Contents | Next

Articles

Coagulation Inhibitor Elicited by Thrombin

Ewa Marciniak 1

1 Department of Medicine, University of Kentucky College of Medicine, Lexington 40506

A protein fraction present in bovine prothrombin complex, or in prothrombin-free preparations obtained from serum, is converted by thrombin into an anticoagulant that strongly interferes with the intrinsic pathway of blood coagulation and with thrombin formation, initiated also by the extrinsic mechanism. If one assumes that a similar phenomenon takes place in vivo, the association between thrombosis and hemorrhage may be better understood.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)