Measurement of Fast Biochemical Reactions
Flow and relaxation methods are being used to study chemical processes in biological macromolecules
Alan N. Schechter 1
1 Laboratory of Chemical Biology, National Institute of Arthritis and Metabolic Diseases, Bethesda, Maryland 20014
In the 4 years since Hammes (87) reviewed, in this journal, the application of flow and relaxation techniques to the study of primary processes in chemical reactions these methods have been applied to a wide range of biochemical problems. These applications have been facilitated by advances in stopped flow and temperature jump instrumentation, especially with respect to the range of physical properties that may be observed during a reaction, and the availability of instruments.