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Science 2 October 1970:
Vol. 170. no. 3953, pp. 73 - 74
DOI: 10.1126/science.170.3953.73

Articles

Pulmonary Hemorrhage in Hamsters after Exposure to Proteolytic Enzymes of Bacillus subtilis

Irene P. Goldring 1, Irving M. Ratner 1, and Leonard Greenburg 1

1 Departments of Surgery, Pathology, and Community Health, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461

Single exposures of Syrian hamsters by aerosol inhalation or intratracheal instillation to proteolytic enzymes of Bacillus subtilis produced massive pulmonary hemorrhage within the first week. Of 46 animals exposed, eight died as a result of extensive hemorrhage. The remainder made uneventful recovery with no apparent residual pulmonary disease 6 weeks after exposure.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Human Experimentation by Industry: The Case of "Enzyme" Detergents.
L. M. LICHTENSTEIN (1971)
Ann Intern Med 75, 964-965
   Abstract »    PDF »



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