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Science 18 September 1970:
Vol. 169. no. 3951, pp. 1213 - 1214
DOI: 10.1126/science.169.3951.1213
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Articles

Tilorone Hydrochloride: An Orally Active Antiviral Agent

Russell F. Krueger 1 and Gerald D. Mayer 1

1 Department of Microbiology, The Wm. S. Merrell Company, Division of Richardson-Merrell Inc., Cincinnati, Ohio 45215

Tilorone hydrochloride, 2,7-bis[2-(diethylamino)ethoxy]fluoren-9-one dihydrochloride, given orally to mice before they are infected is active against at least nine viruses of both RNA and DNA groups. The compound is effective when given prophylactically; the optimum time of treatment depends on the route of infection.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Tilorone Hydrochloride: Mode of Action.
G. D. Mayer and R. F. Krueger (1970)
Science 169, 1214-1215
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Science. ISSN 0036-8075 (print), 1095-9203 (online)