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Science 7 August 1970:
Vol. 169. no. 3945, pp. 603 - 604
DOI: 10.1126/science.169.3945.603
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Articles

Pulmonary Surfactant and Evolution of the Lungs

John A. Clements 1, Jean Nellenbogen 1, and Harold J. Trahan 1

1 Cardiovascular Research Institute and Department of Pediatrics, University of California, San Francisco 94122

Pulmonary surfactant has been looked for and found in 11 representatives of four vertebrate classes. The amount of surfactant, estimated by quantitative spreading as a surface film, correlates well with alveolar surface area and with the amount of saturated, mainly dipalmitoyl, phosphatidylcholine in the lung parenchyma. The quantities of other phospholipids do not correlate well with alveolar surface area.


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