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Science 17 July 1970:
Vol. 169. no. 3942, pp. 296 - 298
DOI: 10.1126/science.169.3942.296
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Articles

Charge-Mosaic Membranes: Dialytic Separation of Electrolytes from Nonelectrolytes and Amino Acids

John N. Weinstein 1 and S. Roy Caplan 1

1 Biophysical Laboratory, Harvard Medical School, Boston, Massachussetts 02115

Charge-mosaic membranes were used for dialytic separations of potassium chloride from low-molecular-weight nonelectrolytes and neutral amino acids. The permeability ratio (potassium chloride to uncharged species) ranged from about 6 in the case of methanol to about 86 in that of mannitol. A theoretical model predicts that optimum rates of dialysis should be achieved by dialyzing against salt concentrations other than zero; this prediction was confirmed by experiment. These observations suggest potential applications of mosaics in laboratory separations, industrial processing, and hemodialysis.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
A New Charge-Mosaic Membrane from a Multiblock Copolymer.
T. FUJIMOTO, K. OHKOSHI, Y. MIYAKI, and M. NAGASAWA (1984)
Science 224, 74-76
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Science. ISSN 0036-8075 (print), 1095-9203 (online)