Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 17 July 1970:
Vol. 169. no. 3942, pp. 291 - 293
DOI: 10.1126/science.169.3942.291
Prev | Table of Contents | Next

Articles

Bone Marrow Histogenesis: A Comparison of Fatty and Red Marrow

Mehdi Tavassoli 1 and William H. Crosby 1

1 Blood Research Laboratory, Tufts-New England Medical Center, Boston, Massachusetts 02111

Histogenesis of fatty marrow in extramedullary sites was compared to histogenesis of the red marrow. Both tissues undergo a similar sequence of events leading to reconstruction of hemopoietic marrow nodules. Histogenesis of yellow marrow then continues; such implants become nodules of fatty marrow, whereas implants of red marrow remain hemopoietically active. This observation supports the concept that histogenesis of the bone marrow recapitulates the ontogeny of this organ and indicates an intrinsic difference between the stroma of red and yellow marrow.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Human Bone Marrow Adipocytes Block Granulopoiesis Through Neuropilin-1-Induced Granulocyte Colony-Stimulating Factor Inhibition.
Z. Belaid-Choucair, Y. Lepelletier, G. Poncin, A. Thiry, C. Humblet, M. Maachi, A. Beaulieu, E. Schneider, A. Briquet, P. Mineur, et al. (2008)
Stem Cells 26, 1556-1564
   Abstract »    Full Text »    PDF »
Analyses of Very Early Hemopoietic Regeneration After Bone Marrow Transplantation: Comparison of Intravenous and Intrabone Marrow Routes.
Q. Li, H. Hisha, R. Yasumizu, T.-X. Fan, G.-X. Yang, Q. Li, Y.-Z. Cui, X.-L. Wang, C.-Y. Song, S. Okazaki, et al. (2007)
Stem Cells 25, 1186-1194
   Abstract »    Full Text »    PDF »
Murine Bone Marrow Stromally Derived BMS2 Adipocytes Support Differentiation and Function of Osteoclast-Like Cells in Vitro.
K. A. Kelly, S. Tanaka, R. Baron, and J. M. Gimble (1998)
Endocrinology 139, 2092-2101
   Abstract »    Full Text »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)