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Science 3 July 1970:
Vol. 169. no. 3940, pp. 68 - 70
DOI: 10.1126/science.169.3940.68
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Articles

Selective Destruction of Target Cells by Diphtheria Toxin Conjugated to Antibody Directed against Antigens on the Cells

Frederick L. Moolten 1 and Sidney R. Cooperband 1

1 Departments of Microbiology and Medicine, Boston University School of Medicine, Boston, Massachusetts 02118

Monkey-kidney cells bearing new surface antigens induced by infection with mumps virus were lysed selectively by diphtheria toxin conjugated to antibody against mumps antigens.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)