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Science 19 June 1970:
Vol. 168. no. 3938, pp. 1458 - 1460
DOI: 10.1126/science.168.3938.1458

Articles

Plasmalemmal and Subsurface Complexes in Human Leukemic Cells: Membrane Bonding by Zipperlike Junctions

Frances T. Sanel 1 and Arthur A. Serpick 1

1 Baltimore Cancer Research Center, National Cancer Institute, U.S. Public Health Service Hospital, 3100 Wyman Park Drive, Baltimore, Maryland 21211

After a brief exposure to agents that provoke phagocytosis, monocytic cells from patients with acute leukemia exhibit pentalaminar and septate membranous complexes. These structures connect plasma membranes of adjacent cells and join surfaces of approximating pseudopodia on the same cell; they also appear to be present in cortical areas of the cytoplasm.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)