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Science 29 May 1970:
Vol. 168. no. 3935, pp. 1100 - 1102
DOI: 10.1126/science.168.3935.1100
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Articles

Blood Concentrations of Acetaldehyde and Ethanol in Chronic Alcoholics

Edward Majchrowicz 1 and Jack H. Mendelson 1

1 National Center for the Prevention and Control of Alcoholism, National Institute of Mental Health, Saint Elizabeths Hospital, Washington, D.C. 20032

Fifteen adult male alcoholic volunteers were studied before, during, and after a 10- to 15-day period of experimentally induced intoxication. Blood acetaldehyde concentrations ranged from 0.11 to 0.15 and from 0.04 to 0.08 milligrams per 100 milliliters when blood ethanol concentrations ranged from 1 to 400 milligrams per 100 milliliters after consumption of bourbon or grain ethanol, respectively. No dose or dose-time relationships were found between blood ethanol concentrations and blood acetaldehyde concentrations during any phase of this study.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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G. L. Aistrup, J. E. Kelly, M. R. Piano, and J. A. Wasserstrom (2006)
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Alcohol Dependence and Opiate Dependence: Lack of Relationship in Mice.
A. Goldstein and B. A. Judson (1971)
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