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Science 29 May 1970:
Vol. 168. no. 3935, pp. 1093 - 1095
DOI: 10.1126/science.168.3935.1093
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Articles

Vasopressin: Effect on Deformability of Urinary Surface of Collecting Duct Cells

Jared J. Grantham 1

1 Department of Medicine, University of Kansas. Medical Center, Kansas City

In isolated renal collecting ducts vasopressin decreased the negative pressure required to suck a hemispherical bulge of the epitheliat cells' urinary surface into the tip of a micropipette. Increased surface deformability may be related to the increased permeability to water which also occurs in the apex of the cells in response to the hormone.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)