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Science 22 May 1970:
Vol. 168. no. 3934, pp. 982 - 984
DOI: 10.1126/science.168.3934.982

Articles

Myxovirus Antibody Increases in Human Connective Tissue Disease

Paul E. Phillips 1 and Charles L. Christian 1

1 Department of Medicine, Columbia University College of Physicians and Surgeons, New York 10032

Antibodies to measles and parainfluenza type 1 viruses were significantly increased in systemic lupus erythematosus and Reiter's syndrome. Of the individuals with highest titers of measles antibody, 75 percent had neurologic illness. Persistent virus infection may be a factor in the pathogenesis of these diseases.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Parainfluenza Viruses.
K. J. Henrickson (2003)
Clin. Microbiol. Rev. 16, 242-264
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False positive IgM antibody tests for human cytomegalovirus (HCMV) in patients with SLE.
F P. Cannavan, L T. Costallat, M B Bertolo, C L Rossi, and S C. Costa (1998)
Lupus 7, 61-62
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Influenza Immunization in Systemic Lupus Erythematosus: A Double-Blind Trial.
G. W. WILLIAMS, A. D. STEINBERG, J. L. REINERTSEN, L. W. KLASSEN, J. L. DECKER, and R. DOLIN (1978)
Ann Intern Med 88, 729-734
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Tubuloreticular Inclusions in Neonatal Lupus Erythematosus.
S. B. Levy, L. A. Goldsmith, M. Morohashi, and K. Hashimoto (1976)
JAMA 235, 2743-2744
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Immunogenetic Analysis and Serum Viral Antibody Titers in Multiple Sclerosis.
J. N. Whitaker, K. L. Herrmann, G. N. Rogentine, S. F. Stein, and L. L. Kollins (1976)
Arch Neurol 33, 399-403
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Virus-Like Structures in Lymphocytes of Patients with Systemic and Discoid Lupus Erythematosus.
J. R. GOODMAN, R. A. SYLVESTER, N. TALAL, and D. L. TUFFANELLI (1973)
Ann Intern Med 79, 396-402
   Abstract »    PDF »
Lupus Erythematosus.
D. L. Tuffanelli (1972)
Arch Dermatol 106, 553-566
   Abstract »    PDF »
Recent Advances in Rheumatic Diseases: The Connective Tissue Diseases Other Than Rheumatoid Arthritis--1970 and 1971.
S. L. WALLACE, H. DIAMOND, and D. KAPLAN (1972)
Ann Intern Med 77, 455-464
   Abstract »    PDF »
Epstein-Barr Virus (Herpes-Type Virus) Antibodies in Connective Tissue Diseases.
D. A. Stevens, M. B. Stevens, G. R. Newell, P. H. Levine, and D. E. Waggoner (1972)
Arch Intern Med 130, 23-28
   Abstract »    PDF »
Illness Resembling Lupus Erythematosus in Mothers of Boys with Chronic Granulomatous Disease.
J. SCHALLER (1972)
Ann Intern Med 76, 747-750
   Abstract »    PDF »
Antibody Titers in Lupus Erythematosus.
P. E. PHILLIPS (1972)
Ann Intern Med 76, 673
   Abstract »    PDF »
Viruses and the Connective Tissue Diseases.
M. ZIFF (1971)
Ann Intern Med 75, 951-958
   Abstract »    PDF »
Intraendothelial Inclusions in Kidneys of Patients with Systemic Lupus Erythematosus.
C. C. TISHER, H. B. KELSO, R. R. ROBINSON, J. C. GUNNELLS, and P. M. BURKHOLDER (1971)
Ann Intern Med 75, 537-547
   Abstract »    PDF »
Articular Manifestations of Systemic Lupus Erythematosus.
R. LABOWITZ and H. R. SCHUMACHER JR. (1971)
Ann Intern Med 74, 911-921
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Science. ISSN 0036-8075 (print), 1095-9203 (online)