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Science 17 April 1970:
Vol. 168. no. 3929, pp. 372 - 373
DOI: 10.1126/science.168.3929.372
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Articles

Acetylcholine Sensitivity of Muscle Fiber Membranes: Mechanism of Regulation by Motoneurons

Douglas M. Fambrough 1

1 Department of Embryology, Carnegie Institution of Washington, Baltimore, Maryland 21210

Inhibitors of RNA and protein synthesis prevent the development of acetylcholine supersensitivity in organ-cultured rat diaphragm muscle but do not affect established acetylcholine sensitivity. The restriction of this sensitivity in innervated muscle apparently involves muscle fibers.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Turnover of Acetylcholine Receptors in Skeletal Muscle.
P. N. Devreotes and D. M. Fambrough (1976)
Cold Spring Harb Symp Quant Biol 40, 237-251
   Abstract »    PDF »
The Biochemical Properties and Regulation of Acetylcholine Receptors in Normal and Denervated Muscle.
J. P. Brookes, D. K. Berg, and Z. W. Hall (1976)
Cold Spring Harb Symp Quant Biol 40, 253-262
   Abstract »    PDF »
Control of ACh Sensitivity in Rat Muscle Fibers.
T. Lomo and R. H. Westgaard (1976)
Cold Spring Harb Symp Quant Biol 40, 263-274
   Abstract »    PDF »
Synaptic Organization and Acetylcholine Sensitivity of Multiply Innervated Autonomic Ganglion Cells.
S. Roper, D. Purves, and U. J. McMahan (1976)
Cold Spring Harb Symp Quant Biol 40, 283-295
   Abstract »    PDF »
Fate of agr-Bungarotoxin Bound to Acetylcholine Receptors of Normal and Denervated Muscle.
D. K. Berg and Z. W. Hall (1974)
Science 184, 473-475
   Abstract »    PDF »
Cholinergic Sensitivity: Normal Variability as a Function of Stimulus Background.
L. Z. Bito, M. J. Dawson, and L. Petrinovi\l=c`\ (1971)
Science 172, 583-585
   Abstract »    PDF »


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