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Science 27 March 1970:
Vol. 167. no. 3926, pp. 1743 - 1745
DOI: 10.1126/science.167.3926.1743
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Articles

Neuronal Correlates of Habituation and Dishabituation of the Gill-Withdrawal Reflex in Aplysia

Irving Kupfermann 1, Vincent Castellucci 1, Harold Pinsker 1, and Eric Kandel 1

1 Departments of Physiology and Psychiatry, New York University Medical School, and Public Health Research Institute of the City of New York, New York

We have examinived the nieural correlates of habittuatiotn atid dishabitiuation of tlhe gill-withdrwal reflex in Aplysia. We obtained intracelllular recordings from identified gill motor neurons in the abdominal ganglionz of a semi-intact preparation of Aplysia wlhile we simultaneously recorded behavior responises of the gill. Habituation and dishabituation were not due to peripheral changes in either the sensory receptors or the gill musculature butt were caused by changes in the amplitlude of the excitatory synaptic potentials produced at the gill motor neurons.


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