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Science 20 February 1970:
Vol. 167. no. 3921, pp. 1139 - 1141
DOI: 10.1126/science.167.3921.1139
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Articles

Fetal Response to Viral Infection: Interferon Production in Sheep

James C. Overall Jr. 1 and Lowell A. Glasgow 1

1 Departments of Microbiology and Pediatrics, University of Rochester School of Medicine, Rochester, N.Y.

When virus was inoculated intravenously during the third trimester, the gestating ewe produced only low amounts of serum interferon, whereas the fetal lamb had the capacity to produce extremely high amounts. There was no evidence of transplacental transfer of interferon between mother and fetus in either direction.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Herpesvirus hominis Infections in the Fetus and the Newborn.
J. B. Hanshaw (1973)
Arch Pediatr Adolesc Med 126, 546-555
   Abstract »    PDF »
Repression of Interferon Action: Induced Dedifferentiation of Embryonic Cells.
S. E. Grossberg and P. S. Morahan (1971)
Science 171, 77-79
   Abstract »    PDF »


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