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Articles
Placental Transfer of a Substituted Pteridine from Fetus to Mother
1 Departments of Medicine (Clinical Pharmacology) and Pharmacology, Emory University School of Medicine, Atlanta, Georgia 30322
In sito near-term sheep placentas transferred triamterene (2,4,7-triamino-6-phenyl-pteridine) from the fetus much more rapidly than to the fetus. This differential transfer effect may significantly influence the distribution of exogenous and endogenous compounds between the maternal and fetal compartments.
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Science. ISSN 0036-8075 (print), 1095-9203 (online)