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Science 13 February 1970:
Vol. 167. no. 3920, pp. 988 - 990
DOI: 10.1126/science.167.3920.988
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Articles

Placental Transfer of a Substituted Pteridine from Fetus to Mother

J. L. McNay 1 and P. G. Dayton 1

1 Departments of Medicine (Clinical Pharmacology) and Pharmacology, Emory University School of Medicine, Atlanta, Georgia 30322

In sito near-term sheep placentas transferred triamterene (2,4,7-triamino-6-phenyl-pteridine) from the fetus much more rapidly than to the fetus. This differential transfer effect may significantly influence the distribution of exogenous and endogenous compounds between the maternal and fetal compartments.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Diphenylhydantoin Intoxication During Pregnancy: A Chemical Study of Drug Distribution in the Albino Rat.
B. Westmoreland and N. H. Bass (1971)
Arch Neurol 24, 158-164
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Science. ISSN 0036-8075 (print), 1095-9203 (online)