Insulin-Stimulated Glucose Uptake by Subcellular Particles from Adipose Tissue Cells
Donald B. Martin 1 and
James R. Carter Jr. 1
1 Diabetes Untit, Massachusetts General Hospital, Boston 02114
Microsomal particles prepared from isolated rat adipose cells take up D-glucose more rapidly than L-glucose. The rate of D-glucose uptake, but not that of L-glucose, is stimulated by incubation of the intact cells with insulin at concentrations as low as 10 microunits per milliliter before disruption and preparation of the microsomes.