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Science 9 January 1970:
Vol. 167. no. 3915, pp. 205 - 207
DOI: 10.1126/science.167.3915.205
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Articles

Polyinosinic-Polycytidylic Acid Inhibits Chemically Induced Tumorigenesis in Mouse Skin

H. V. Gelboin 1 and H. B. Levy 2

1 Nationial Cancer Institute, Bethesda, Maryland 20014
2 Nationial Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20014

Polyinosinic-polycytidylic acid administered intraperitoneally inhibits (i) the formation of skin tumors induced by a single topical application of 9,10-dimethylbenzanthracene followed by weekly applications of croton oil and (ii) the formation of skin tumors induced by a single large application of 9,10-dimethylbenzanthracene.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Tumorigenesis in Mouse Skin: Inhibition by Synthetic Inhibitors of Proteases.
W. Troll, A. Klassen, and A. Janoff (1970)
Science 169, 1211-1213
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Science. ISSN 0036-8075 (print), 1095-9203 (online)