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Science 9 January 1970:
Vol. 167. no. 3915, pp. 181 - 182
DOI: 10.1126/science.167.3915.181
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Articles

L-Asparaginase-Deficient Mutants of Yeast

Gary E. Jones 1 and Robert K. Mortimer 1

1 Division of Medical Physics, University of California, Berkeley 94720

Yeast L-asparaginase is a multimeric enzyme for which only a single structural gene has been found. Fourteen mutants deficient in L-asparaginase have been isolated, and they have been located at one site on the genetic map of Saccharomyces cerevisiae. The L-asparaginase gene (aspl) is located about 18 centimorgans from a gene governing tryptophan synthesis (trp4) on fragment 2 of the map.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)