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Science 2 January 1970:
Vol. 167. no. 3914, pp. 80 - 82
DOI: 10.1126/science.167.3914.80
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Articles

Animal Cells: Noncorrelation of Length of G1 Phase with Size after Mitosis

Thomas O. Fox 1 and Arthur B. Pardee 1

1 Moffett Laboratory, Princeton University, Printceton, New Jersey 08540

The interval between mitosis and initiation of DNA synthesis (G1) varied over a fourfold range for Chinese hamster ovary cells, an established line. This was not because of size differences. Synchlronous cells of different sizes began DNA synthesis at similar times after mitosis. A novel technique of centrifugation for separating cells according to size is described.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Does size matter?.
W. A. Wells (2002)
J. Cell Biol. 158, 1156-1159
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Equilibrium Density-Gradient Procedure for Selection of Synchronous Cells from Asynchronous Cultures.
T. O. Sitz, A. B. Kent, H. A. Hopkins, and R. R. Schmidt (1970)
Science 168, 1231-1232
   Abstract »    PDF »


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