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Science 19 December 1969:
Vol. 166. no. 3912, pp. 1540 - 1541
DOI: 10.1126/science.166.3912.1540
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Articles

Ecdysone Analog: Conversion to Alpha Ecdysone and 20-Hydroxyecdysone by an Insect

J. N. Kaplanis 1, W. E. Robbins 1, M. J. Thompson 1, and A. H. Baumhover 2

1 Insect Physiology Laboratory, U.S. Agriculture Research Service, Beltsville, Maryland 20705
2 Entomology Research Division, U.S. Agriculture Research Service, Oxford, North Carolina 27565

The tritium-labeled synthetic ecdysone analog Dgr7-5beta-cholestene-2beta,-3beta,14agr-triol-6-one terminated diapause when injected into diapausing tobacco hornworm pupae and was converted into tritium-labeled agr-ecdysone and tritium-labeled 20-hydroxyecdysone. About half of the crystalline agr-ecdysone and 20-hydroxyecdysone isolated from the tobacco hornworms 7frac12 to 8frac12 days after injection was derived from endogenous steroid precursors and half from the transformation of the synthetic ecdysone analog.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
26-Hydroxyecdysone: New Insect Molting Hormone from the Egg of the Tobacco Hornworm.
J. N. Kaplanis, W. E. Robbins, M. J. Thompson, and S. R. Dutky (1973)
Science 180, 307-308
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Science. ISSN 0036-8075 (print), 1095-9203 (online)