Ecdysone Analog: Conversion to Alpha Ecdysone and 20-Hydroxyecdysone by an Insect

doi:10.1126/science.166.3912.1540

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Science 19 December 1969:
Vol. 166. no. 3912, pp. 1540 - 1541
DOI: 10.1126/science.166.3912.1540

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Ecdysone Analog: Conversion to Alpha Ecdysone and 20-Hydroxyecdysone by an Insect

J. N. Kaplanis ¹, W. E. Robbins ¹, M. J. Thompson ¹, and A. H. Baumhover ²

¹ Insect Physiology Laboratory, U.S. Agriculture Research Service, Beltsville, Maryland 20705
² Entomology Research Division, U.S. Agriculture Research Service, Oxford, North Carolina 27565

The tritium-labeled synthetic ecdysone analog $Dgr$ ⁷-5 $beta$ -cholestene-2 $beta$ ,-3 $beta$ ,14 $agr$ -triol-6-oneterminated diapause when injected into diapausing tobacco hornwormpupae and was converted into tritium-labeled $agr$ -ecdysone and tritium-labeled20-hydroxyecdysone. About half of the crystalline $agr$ -ecdysoneand 20-hydroxyecdysone isolated from the tobacco hornworms 7 $frac12$ to 8 $frac12$ days after injection was derived from endogenous steroidprecursors and half from the transformation of the syntheticecdysone analog.

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:

26-Hydroxyecdysone: New Insect Molting Hormone from the Egg of the Tobacco Hornworm.: J. N. Kaplanis, W. E. Robbins, M. J. Thompson, and S. R. Dutky (1973)
Science 180, 307-308
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