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Science 28 November 1969:
Vol. 166. no. 3909, pp. 1154 - 1156
DOI: 10.1126/science.166.3909.1154
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Articles

Intestinal Calcium Absorption: Nature of Defect in Chronic Renal Disease

Louis V. Avioli 1, Susan Scott 1, Sook Won Lee 1, and H. F. De Luca 2

1 Department of Medicine, Washington University School of Medicine, and Jewish Hospital of St. Louis, St. Louis, Missouri 63110
2 Department of Biochemistry, University of Wisconsin, Madison

When compared to that of normal animals, calcium-binding protein activity of duodenal mucosa obtained from uremic rats was decreased. There was no change in this activity after vitamin D3, therapy. In contrast, prior treatment with 25-hydroxycholecalcijerol resulted in increased transport of calcium-45 and calcium-binding protein activity in the intestine.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Intestinal Absorption of Calcium.
L. V. Avioli (1972)
Arch Intern Med 129, 345-355
   Abstract »    PDF »
Vitamin D Metabolism: The Role of Kidney Tissue.
R. Gray, I. Boylf, and H. F. Deluca (1971)
Science 172, 1232-1234
   Abstract »    PDF »
Uremic Toxins and Mineral Metabolism: Potential Sites of Interaction.
H. J. Gitelman (1970)
Arch Intern Med 126, 793-800
   Abstract »    PDF »
Effect of Chronic Uremia on Collagen Metabolism in Skin and Bone.
T. J. Hahn and L. V. Avioli (1970)
Arch Intern Med 126, 882-886
   Abstract »    PDF »
The Nature of Vitamin D Resistance in Experimental Uremia.
D. V. Kimberg, R. D. Baerg, and E. Gershon (1970)
Arch Intern Med 126, 891-895
   Abstract »    PDF »
Treatment of Renal Osteodystrophy With 25-Hydroxycholecalciferol.
H. F. DeLuca and L. V. Avioli (1970)
Arch Intern Med 126, 896-899
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)