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Science 31 October 1969:
Vol. 166. no. 3905, pp. 629 - 631
DOI: 10.1126/science.166.3905.629
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Articles

Phosphorylation of Dipteran Chromosomes and Rat Liver Nuclei

William B. Benjamin 1 and Reba M. Goodman 2

1 University of Pennsylvania School of Medicine, Philadelphia
2 International Institute for the Study of Human Reproduction, Columbia University College of Physicians and Surgeons, New York 10032

Side-chain modifications of the nucleoproteins are believed to be involved in the control of gene function. Rat liver nuclei and chromatin incubated in adenosine triphosphate labeled in the gamma position with phosphorus-32 demonstrated rapid phosphorylation in vitro of the nuclear proteins. Dipteran salivary glands incubated in either labeled adenosine triphosphate or ortho-phosphate labeled with phosphorus-32 showed that there is phosphorylation of chromosomal protein. The phosphorus is associated in protein from both liver and salivary gland nuclei predominantly with phosphoserine.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Phosphorylation of DNA-binding Nuclear Acidic Proteins and Gene Activation in the HeLa Cell Cycle.
V. G. Allfrey, A. Inoue, J. Karn, E. M. Johnson, and G. Vidali (1974)
Cold Spring Harb Symp Quant Biol 38, 785-801
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Science. ISSN 0036-8075 (print), 1095-9203 (online)