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Science 10 October 1969:
Vol. 166. no. 3902, pp. 250 - 251
DOI: 10.1126/science.166.3902.250
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Articles

Keratohyalin: Extraction and in vitro Aggregation

Arthur R. Ugel 1

1 Dermatology Branch, National Cancer Institute, Bethesda, Maryland

Kercatohyalin can be extracted from epidermis by 1.0 molar phosphate buffer (pH 7.0), as demonstrated histochemically and ultrastructurally. If the extracted material is dialyzed against water, it aggregates to form granules that are similar to keratolhyalin granules in size, shape, histochemical staining, and electron opacity.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)