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Science 3 October 1969:
Vol. 166. no. 3901, pp. 110 - 111
DOI: 10.1126/science.166.3901.110
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Articles

Visceral and Behavioral Responses to Intraduodenal Fat

John W. Fara 1, Eduardo H. Rubinstein 1, and Ralph R. Sonnenschein 1

1 Department of Physiology, University of California School of Medicine, Los Angeles 90024

Introduction of milk or corn oil into the duodenum of the cat evokes an increase in superior mesenteric blood flow (blocked by atropine), an inhibition of gastric and duodenal motility, and sedation. Cholecystokinin-pancreozymin mimics the mesenteric vascular effect of intraduodenal fat and seems to have a sedating action.


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