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Science 19 September 1969:
Vol. 165. no. 3899, pp. 1271 - 1273
DOI: 10.1126/science.165.3899.1271
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Articles

Retention of Delayed-Alternation: Effect of Selective Lesions of Sulcus Principalis

Nelson Butters 1 and Deepak Pandya 1

1 Veterans Administration Hospital and Boston University School of Medicine, Boston, Massachusetts 02130

Monkeys with bilateral lesions of the anterior, miiddle, or posterior thirds of the principal sulcus, of the periarcuate prefrontal region, or of the inferior parietal lobule were tested for retention of spatial delayed-alternation. Lesions limited to the middle third of sulcus principalis resulted in failure to relearn delayedalternation within 1000 trials; lesions elsewhere had little effect.


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