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Science 29 August 1969:
Vol. 165. no. 3896, pp. 913 - 914
DOI: 10.1126/science.165.3896.913
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Articles

Micelle Formation between 5-Hydroxytryptamine and Adenosine Triphosphate in Platelet Storage Organelles

K. H. Berneis 1, M. Da Prada 1, and A. Pletscher 1

1 F. Hoffmann-La Roche & Co. Ltd., Basle, Switzerland

As judged by analytical ultracentrifugation, 5-hydroxytryptamine and adenosine-5'-triphosphate form micelles in artificial mixtures and also in storage organelles containing 5-hydroxytryptamine of blood platelets of rabbits. Their average apparent molecular weights depend on the concentration and on the molar ratio of the two constituents. The 5-hydroxytryptamine and adenosine triphosphate of these 5-hydroxytryptamine organelles may be stored in vivo together as micelles with apparent molecular weights of several hundred thousands or more.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)