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Science 22 August 1969:
Vol. 165. no. 3895, pp. 816 - 817
DOI: 10.1126/science.165.3895.816
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Articles

Hepatitis in Marmosets: Induction of Disease with Coded Specimens from a Human Volunteer Study

Albert W. Holmes 1, Lauren Wolfe 1, Howard Rosenblate 1, and Friedrich Deinhardt 1

1 Departments of Medicinie and Microbiology, Presbyterian-St. Luke's Hospital, Chicago, Illinois 60612

Marmosets inoculated with plasma from three early acute hepatitis patients developed hepatitis 30 to 40 days later. Other groups of marmosets receiving preinfection plasmas from the same patients showed no evidence of hepatitis in this experiment. It is, therefore, most probable that hepatitis in marmosets represented transmission of human disease rather than activation of latent "marmoset hepatitis."


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Hepatitis A: Old and New.
J. A. Cuthbert (2001)
Clin. Microbiol. Rev. 14, 38-58
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Viral Hepatitis: Clinical and Tissue Culture Studies.
J. D. Boggs, J. L. Melnick, M. E. Conrad, and B. F. Felsher (1970)
JAMA 214, 1041-1046
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Viral Hepatitis.
N. R. SHULMAN, R. J. HIRSCHMAN, and L. F. BARKER (1970)
Ann Intern Med 72, 257-269
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Science. ISSN 0036-8075 (print), 1095-9203 (online)