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Articles
Estradiol: Specific Binding by Pituitary Nuclear Fraction in vitro
1 Department of Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45219
The nuclear fraction of a homogenate of anterior pituitary has a marked binding affinity for estradiol but not for other hormonal steroids. Characteristics of the uptake of estradiol by pituitary nuclear fraction are like those reported for the uterus. Study in vitro will be useful in elucidating how direct estrogen feedback control of anterior pituitary function is mediated.
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Science. ISSN 0036-8075 (print), 1095-9203 (online)