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Science 25 July 1969:
Vol. 165. no. 3891, pp. 396 - 398
DOI: 10.1126/science.165.3891.396
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Articles

Immune Adherence by the Fourth Component of Complement

Neil R. Cooper 1

1 Department of Experimental Pathology, Scripps Clinic and Research Foundation La Joll, California 92037

An immune complex becomes reactive in immune adherence after the specific binding of the fourth component of complement (C4). Immune adherence produced by the fourth component of complement is indistinguishable from classical immune adherence in terms of all parameters tested, except that it is entirely independent of the participation of the second and third components of complement.


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