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Science 11 July 1969:
Vol. 165. no. 3889, pp. 194 - 196
DOI: 10.1126/science.165.3889.194
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Articles

Electron Microscopic Radioautography: Identification of Origin of Synaptic Terminals in Normal Nervous Tissue

Anita Hendrickson 1

1 Department of Ophthalmology, University of Washington, Seattle 98105

A method combining intraocular injection of tritiated leucine and electron microscopic radioautography has been used to study the distribution of optic nerve terminals in the monkey lateral geniculate nucleus. Radioactive label is found in only one type of synaptic terminal, which demonstrates that this terminal is of retinal origin and that this approach can be used to study the origin of synaptic terminals in normal tissue.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Radioautography of the Optic Tectum of the Goldfish after Intraocular Injection of [3H]Proline.
J. H. Neale, E. A. Neale, and B. W. Agranoff (1972)
Science 176, 407-410
   Abstract »    PDF »
Transneuronal Transfer of Radioactivity in the Central Nervous System.
B. Grafstein (1971)
Science 172, 177-179
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)