Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 4 July 1969:
Vol. 165. no. 3888, pp. 81 - 83
DOI: 10.1126/science.165.3888.81
Prev | Table of Contents | Next

Articles

Blood-Brain Barrier: Evidence for Active Cation Transport between Blood and the Extraceliular Fluid of Brain

Laszlo Z. Bito 1

1 Ophthalmology Research, Columbia University School of Medicine, New York 10032

The concentration gradients of Mg++ and K+ in the cerebrospinal fluid system indicate that the (Mg++) is higher and the (K+) is lower in the extra-cellular fluid of the cerebral cortex than the concentrations of these cations in either plasma-dialysate or cisternal fluid. Such cation distribution demonstrates the existence of an active transport process across the blood-brain barrier.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)