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Science 27 June 1969:
Vol. 164. no. 3887, pp. 1519 - 1521
DOI: 10.1126/science.164.3887.1519
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Articles

Glomerular Sialoprotein

Steven C. Mohos 1 and Lorant Skoza 1

1 Department of Pathology, New York Medical College, Fifth Avenue and 106th Street, New York 10029

The high content of sialic acid in the glomerulus is associated with the cell membrane of epithelial cells lining the basement membrane. Whereas enzyme studies indicate that sialic acid is a determinant of the nephritogenic antigen, the physicochemical properties of this nephritogenic glycoprotein suggest that sialic acid may have an important role in the filtration mechanism.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)