Venom Neutralization by Rattlesnake Serum Albumin
William C. Clark 1 and
Harold K. Voris 2
1 Yale College, New Haveni, Conniecticut 06520
2 Department of Biology, Yale University, New Haven, Connecticut
The blood serum of the eastern diamond back rattlesnake (Crotalus adamanteus) neutralizes lethal doses of C. adamanteus venom in mice. The protective capacity of the serum is associated with the serum albumin, rather than the immunoglobulin fraction of the blood. Neither the serum nor its albumin fraction form precipitin bands on immunophoresis against venom.